A more detailed analysis revealed that NLRP3 mRNA expression was significantly increased in patient samples categorized as monocytic M4 and M5 FAB subtypes compared to undifferentiated (M0) or erythroblastic leukemia (M6) (Fig. 1B, data from the NCBI-GEO GSE12417, platform GPL570). This evidence concerns the gene NLRP3 and acute erythroid leukemia.