It is worth noting that miR-125b-5p is a vital suppressor miRNA that can target peroxiredoxins like 2 A (PRXL2A), signal transducer and activator of transcription 3 (STAT3), matrix metalloproteinase-2 (MMP2), and others to induce tumor cell death or increase drug sensitivity [17–19]. Here, PRXL2A is linked to neoplasm.