As elegantly demonstrated in Figure 3A, the frequency of mMDSCs distinctly surged in HCC patients with an AFP level exceeding 400 ng/mL, in stark contrast to those with AFP levels at or below 400 ng/mL (5.76 ± 2.58% vs. 4.24 ± 2.74%, p = .0166). This evidence concerns the gene AFP and hepatocellular carcinoma.