Finalized age (HR = 1.04, 95% CI: 1.01–1.07; P = 0.003), COPD (HR = 2.91, 95% CI: 1.26–6.71; P = 0.012), hyperthyroidism (HR = 3.59, 95% CI: 1.59–8.10; P = 0.002), renal dysfunction (HR = 2.55, 95% CI: 1.43–4.56; P = 0.002), LAD (HR = 3.02, 95% CI: 1.57–5.82; P = 0.001), and PASP (HR = 1.04, 95% CI: 1.03–1.06; P < 0.001) were the six factors identified as the NOAF independent predictors (Table 2). This evidence concerns the gene CPB1 and hyperthyroidism.