Drug-induced aseptic meningitis (DIAM) is a rare but well-documented cause of aseptic meningitis, presenting as an adverse reaction to various medications, including non-steroidal anti-inflammatory drugs (NSAIDs), antibiotics, immune checkpoint inhibitors (ICIs), cyclooxygenase-2 (COX-2) inhibitors, and monoclonal antibodies [1,2]. The gene discussed is PTGS2; the disease is aseptic meningitis.