After adding the results of the CMPEC, results suggested AST (pooled OR = 1.19, 95% CI = 1.08 ~ 1.31, p < 0.001), ALT (pooled OR = 1.07, 95% CI:1.04~1.11, p < 0.001), ALP (pooled OR = 1.35, 95% CI:1.02~1.77, p = 0.34), and low TP (pooled OR = 1.32, 95% CI:1.08~1.61, p = 0.007) were positively related to the risk of GSD, while high ALB (pooled OR = 0.54, 95% CI:0.48~0.60, p < 0.001) were negatively related to the risk of GSD. The gene discussed is GPT; the disease is disorder of glycogen metabolism.