Immunohistochemically, the positive expression of PEComa include melanocytic markers (HMB 45, Melan-A, S-100), myogenic markers (SMA) and angiogenic markers (CD34), and negative expressions include AFP, Hep-Par1, CD117, CK8/18, and TFE-3 (3, 9, 13, 25). The gene discussed is MLANA; the disease is neoplasm with perivascular epithelioid cell differentiation.