The model was used to stratify a dataset composed of 31 ovarian or breast cancers with confirmed BRCA1/2 mutations and 84 cases negative for mutations in BRCA1/2 or any of the 12 selected genes implicated in HR, providing an AUROC of 0.984, a sensitivity of 90%, and a specificity of 98%. Here, BRCA1 is linked to breast carcinoma.