miR-124 and miR-145 inhibit the migration of glioma cells and self-renewal of glioma stem cells by targeting SCP-1 and SOX2, relatively.miR-124-3p is reported to suppress glioma proliferation through the FLOT2/AKT1 pathway.miR-145 can reduce the activity of Bcl-X(L) in prostate cancer cells, thereby suppressing cell proliferation and promoting tumor apoptosis. Here, FLOT2 is linked to Familial prostate cancer.