VCAN and breast cancer: A study examining methylation patterns in BC found that hypermethylation of Janus kinase 3 (JAK3) and hypomethylation in EYA4, GATA6, and SOX1 was associated with LG intermediate-risk nonmuscle-invasive bladder cancer (LG NMIBC), while hypermethylation of CSPG2, HOXA11, HOXA9, HS3ST2, SOX1, and TWIST1 was linked to muscle-invasive bladder cancer (MIBC).