Similarly, aberrant DNA methylation at FGFR3 and TP53 promoter in NMIBC shows that male gender (HR = 9.97; p = 0.008), HG (HR = 2.97; p = 0.043), and pT1 stage (HR = 0.08; p = 0.031) are an independent predictor of RFS, whereas HG tumor (HR = 3.99; p = 0.042) and pT1 stage (HR = 2.48; p = 0.043) are an important prognostic indicator for PFS. The gene discussed is FGFR3; the disease is neoplasm.