TGFB1 and myopia: It was found that the expression of corneal extracellular matrix and collagen I, III, V, and VIII-related proteins were increased in female patients, as well as the expression of TGF-β and Smad protein-related signaling pathways, suggesting that corneal extracellular matrix remodeling and collagen fiber synthesis may be more active in female patients, and thus the changes in the cornea of female patients may contribute to the onset and progression of myopia.