As for immune escape, after coculturing the NPC cells with T cells, knockdown of ELF3 induced NPC cell apoptosis (Fig. 9A), along with a promotion in the secretion of effectors by T cells in the coculture system (Fig. 9B), and a rise in the percentage of cytotoxic T cell activation (Fig. 9, C and D). This evidence concerns the gene ELF3 and nasopharyngeal carcinoma.