Plasma MMP-8 was elevated in participants with confirmed TB who died compared to those who survived (median, 32 811 pg/mL [IQR, 12 060–66 934 pg/mL] vs 20 201 pg/mL [IQR, 6050–40 561 pg/mL]; P = .002; Figure 1D). This evidence concerns the gene MMP8 and tuberculosis.