To determine whether CMTM6 knockdown influenced glucose uptake by CRC cells, CRC cells were incubated with the fluorescent glucose analog 2-(N-[7-nitrobenz-2-oxa-1,3-diazol-4-yl] amino)-2-deoxyglucose (2-NBDG), and flow cytometry was subsequently performed to quantify 2-NBDG uptake by the cells. Here, CMTM6 is linked to colorectal carcinoma.