To this end, HCT116 cells overexpressing CMTM6-HA and Rab11-FLAG were subjected to triple IF, and the results revealed that Glut1 (green) and CMTM6 (purple) colocalized with endosomes (arrowheads, Fig. 5a) and the PM (arrows, Fig. 5a) of CRC cells. This evidence concerns the gene CMTM6 and colorectal carcinoma.