Out of 130 patients, 17 had ALDH1 markers and 49 were CTC-positive.45 CD44, a cell surface glycoprotein implicated in metastasis and cell migration,46 characterizes a subpopulation of breast CSCs capable of intravasating into the bloodstream, identified by the CD44+/CD24low/–/Lin–markers.47 In colorectal cancer, CSCs expressing CD44v6 are associated with metastatic potential.48 Additionally, CSCs have decreased levels of certain glycosphingolipids that are important for cell growth and motility, such as Fuc-(n) Lc4Cer and Gb3Cer, while elevated levels of GD2, GD3, GM2, and GD1a are seen. This evidence concerns the gene CD44 and colorectal cancer.