SREBF1 and hepatocellular carcinoma: MCT1–mediated lactate uptake promotes ATP production and inactivates AMPK in hepatocellular carcinoma, resulting in upregulation of sterol regulatory element binding protein 1 (SREBP1) and stearoyl-CoA desaturase 1 (SCD1), thereby promoting production of the MUFAs against ferroptosis [61].