In 2012, Dixon and Stockwell discovered that ferroptosis could be induced by inhibition of SLC7A11- mediated cystine uptake by erastin or depletion of cystine [1], and inhibition of SLC7A11 activity through cystine starvation, gene silencing, or use of inhibitors has been shown to induce ferroptosis in various cell types, including cancer cells. Here, SLC7A11 is linked to cancer.