AIP and Neoplasm of the endocrine system: All of the gonadotroph PitNET showed in both, the primary and the recurrent lesions, SNV in the AIP (Aryl hydrocarbon receptor interacting protein rs64108, c.C682A, p.Q228K) and MEN1 (Multiple endocrine neoplasia type 1 rs2959656, c.A1621G, p.T541A) genes (Fig. 1D–F).