In addition to being found in all cases of crescentic (pauci-immune) GN (10/10), crescents were also identified in Anti-GBM disease (3/3), IgA nephropathy (3/13, with 2/3 Henoch Schoenlein purpura (HSP) cases), Membranoproliferative glomerulonephritis (MPGN) (3/5), and mixed pathology with features of IgA/MPGN/Membranous nephropathy (1/3). This evidence concerns the gene CD79A and hereditary spastic paraplegia.