It has been determined that APX expression and protein activity are manipulated in response to pathogen infection (Pérez‐Clemente et al., 2014; Zhang, Song, et al., 2023), while the reduction of APX activity results in ROS accumulation, thereby enhancing plant innate immunity (Chandrashekar & Umesha, 2014; Fujiwara et al., 2016). The gene discussed is APEX1; the disease is infection.