We also assessed the protein level of USP36 in breast cancer patient samples using immunohistochemistry (IHC), interestingly, Breast cancers also showed significant increases in USP36 expression (11/55 vs 43/65; P < 0.001; Fig. 1G-H) which was consistent with the result from TCGA database (Fig. 1C). The gene discussed is USP36; the disease is breast carcinoma.