Moreover, IL-6, IL-17, and IL-35 levels were associated with periodontitis (OR = 1.344, 95% CI = 1.159–1.56; OR = 1.063, 95% CI = 1.025–1.102; OR = 1.261, 95% CI = 1.110–1.434, respectively) (p < 0.001, p = 0.001, p < 0.001, respectively). This evidence concerns the gene IL6 and periodontitis.