Furthermore, we used the specific inhibitor of IGF2BP2, CWI1-2, and found that 5 μM and 10 μM of HF relieved the inhibitory effect of CWI1-2, suggesting that HF could act as an activator of IGF2BP2 (26) (Fig. 5, K and L). Here, IGF2BP2 is linked to hydrops fetalis.