This analysis further defined a shift away from IL10 innate sender cellular subsets toward IL10 adaptive immune cell subpopulations: GZMKhi TEM/PEX-like and NK-like cells, relative to naive granulomas, with these two T, NK cell subsets targeting several T, NK cells subsets (Tc17-like, T1T17-like, Tregs) (Figure 7F). Here, IL10 is linked to Granuloma.