MKI67 and neoplasm: Retrospective studies of patients treated with PRRT followed by surgery for oligometastatic (less than 3 liver metastases) or potentially resectable high-risk NF-pNETs (such as Ki-67 index greater than 10%, size greater than 4 cm, invasion into nearby organs, or vascular invasion) have reported reductions in tumour size and pathological tumour response13,14.