AR and partial androgen insensitivity syndrome: Of these 57 reported cases of PAIS, the diagnosis had been genetically confirmed in 45 (79%) with 32 different AR variants (Table 1) of which 4 (12%) were located in the N-terminal domain (NTD), 7 (22%) in the DNA-binding domain (DBD), and the remaining 21 (66%) in the ligand-binding domain (LBD).