LASP1 and diabetes mellitus: LncRNA MIAT was originally discovered in a genome-wide association study of Japanese patients with myocardial infarction.[47] MIAT has been found to act as a sponge for miR-150-5p, thereby contributing to the development of thyroid, cervical, ovarian, and diabetes-induced microvascular dysfunction.[48–51] Furthermore, it has been reported that the MIAT-miR-324-3p-LASP1 pathway plays a significant role in promoting the proliferation and invasion of thyroid cancer, with its activation being closely associated with the inactivation of PI3K/AKT signal transduction.[52]