Volcano plots of genes expressed by mast cells (Cd11b-Cma1+Fcer1a+) and basophils (Cd11b+Mcpt8+Fcer1a+) showed that, in comparison, basophils expressed higher levels of cytokines/chemokines, such as Il4, Il13, and Il6, and mast cells expressed higher levels of Ccl2 and Ccl7 (Figure 3C), revealing their differential immune responses in ACD. The gene discussed is IL13; the disease is granular corneal dystrophy type II.