A study investigating the differential involvement of chemokines in chemical-induced allergic skin responses compared to irritant skin responses showed that CXCL9 and CXCL10 were among the top five chemokines that were uniquely upregulated in hapten-induced skin allergic inflammation but were absent in inflammation triggered by irritants (Meller et al., 2007). This evidence concerns the gene CXCL9 and neoplasm.