Volcano plots of genes expressed by mast cells (Cd11b-Cma1+Fcer1a+) and basophils (Cd11b+Mcpt8+Fcer1a+) showed that, in comparison, basophils expressed higher levels of cytokines/chemokines, such as Il4, Il13, and Il6, and mast cells expressed higher levels of Ccl2 and Ccl7 (Figure 3C), revealing their differential immune responses in ACD. This evidence concerns the gene CCL7 and granular corneal dystrophy type II.