MAP1LC3A and lung cancer: To determine whether direct inhibition of KRASG12C in lung cancer cells influences autophagy, human KRASG12X-driven lung cancer cell lines were engineered to express a chimeric fluorescent autophagy reporter (FAR) comprised of mCherry fused to EGFP fused to LC3 (Kinsey et al., 2019; Kimura et al., 2007).