Although α-synA53T;TDP-43,α-synA53T, Taupro-agg and α-synA53T;Aβ1-42;Taupro-agg are all LBD models, their PD phenotypes were much milder than α-synA53T and α-synA53T;Aβ1-42. This evidence concerns the gene TARDBP and Parkinson disease.