The results of multivariate logistic regression analysis adjusted by age, hypertension, diabetes, cardiovascular disease, liver disease and renal disease variables showed that the association between IL-10 (OR [95% CI] 2.20 [1.78–2.71]) and NEWS (OR [95% CI] 1.92 [1.57–2.34]) remained consistent across sepsis development (Table S1; Figure 2A). The gene discussed is IL10; the disease is Hypertension.