ITPRIPL1 and adrenal cortex carcinoma: High expression of ITPRIPL1 was strongly associated with shorter OS in ACC (OS: HR = 2.763, P = 0.002), KICH (OS: HR = 5.414, P = 0.003), LGG (OS: HR = 1.646, P = 0.000) and SARC (OS: HR = 1.435, P = 0.000), but was a protective factor for BRCA (OS: HR = 0.742, P = 0.010), head and neck squamous cell carcinoma (HNSC) (OS: HR = 0.804, P = 0.007) and THYM (OS: HR = 0.334, P = 0.007) (Figure 3A).