GPT and Tangier disease: A previous report has also described iron overload in two folate-deficient patients [22], and our patient did not have any risk factors to suggest another etiology such as chronic liver disease (denied excessive alcohol intake, had a temporarily mildly elevated alanine aminotransferase, and had no significant hepatic abnormality on imaging), secondary iron overload (has never required transfusions before), or hemochromatosis (no characteristic physical findings or family history) [23].