CD209 and infection: We have further shown that Gx-psDiMan canpotently block cell surface DC-SIGN-augmented EBOV-GP-driven viruscellular entry with sub-nM to mid-pM level of EC50 values.Such low EC50 values place them among the most potent glycoconjugateinhibitors against DC-SIGN-mediated virus entry into host cells.12−14,18,20 Consistent with their solution MLGI affinities, Gx-psDiMan exhibits no apparent or only weak inhibition against DC-SIGNR-promotedviral infection.