The logistic regression (LR) models achieved favorable AUC values in the training set (0.875, 95% CI: 0.833-0.966) and testing set (0.845, 95% CI: 0.661-0.979), indicating that radiological analysis using DCE-MRI images can effectively distinguish between HER2-low and HER2-zero BC subtypes. Here, ERBB2 is linked to breast cancer.