Age, sex, ECOG score, Lugano stage, B symptoms, pathological subtypes, IPI score, leukocyte, serum LDH, albumin, β2 microglobulin, Ki-67, lymphoma site, first-line treatment and other indicators of 88 PI-DLBCL patients were included in the COX regression model for PFS univariate analysis. The gene discussed is HLA-G; the disease is lymphoma.