FF of adolescent patients with cancer had decreased levels of nine cytokines (G-CSF, EGF, FGF-7, BDNF, BLC, LIGHT, MCP-2, IL-7, TGF-beta 1) and increased levels of one cytokine (MCP-1) compared to FF of adolescents without cancer (Supplementary Fig. S13B). The gene discussed is BDNF; the disease is cancer.