HLA-C and central nervous system cancer: To investigate the impact of SIGLEC7 on the inflammatory response in glioma, we conducted expression analyses of several immunoproteins of significance, including hematopoietic cell kinase (HCK), immunoglobulin G (IgG), interferon, lymphocyte-specific kinase (LCK), major histocompatibility complex (MHC), and signal transducer and activator of transcription 1/2 (STAT1/2) (18).