The ADAM10 expression was associated with immune invasion in 15 neoplasm species according to the stromal score, indicating 12 significant positive associations (TCGA-BRCA, TCGA-LUAD, TCGA-KIPAN, TCGA-COAD, CGA-COADREAD, TCGA-HNSC, TCGA-KIRC, TCGA-LUSC, TCGA-READ, TCGA-OV, TCGA-PAAD, and TCGA-acute myeloid leukemia) and three significant negative associations (TARGET-WT, TCGA-SKCM-P and TCGA-BLCA) when analyzing the association between ADAM10 and immune infiltration markers in 10,179 specimens from 44 cancer types (Figure 8; Table 2). The gene discussed is ADAM10; the disease is acute myeloid leukemia.