Moreover, the expression of ADAM10 was reciprocally exclusive with some tumor immune checkpoint genes, such as VEGFB, LAG3, IL4, TNFRSF18, TNFRSF4, TNF receptor superfamily member 14 (TNFRSF14), CD27, CCL5, etc. (Figure 6B). The gene discussed is CCL5; the disease is neoplasm.