A cocktail of 5 strains of Bifidobacteria were shown to cause a decline in expressions of genes involved in tumor progression such as EGFR by 4.4 folds, HER-2 by 6.7 folds, and PTGS-2 by 20 folds and induced apoptosis in LS174T CRC cells. Here, ERBB2 is linked to colorectal carcinoma.