The combination of SCFAs such as 67.5 mM acetate, 40 mM butyrate, 25.9 mM propionate administered orally into colitis-associated AOM/DSS-induced CRC male BALB/c mice model decreased the tumor incidence and size, improved inflammation of the colon and suppressed the expression of proinflammatory cytokines such as IL-6, TNF-α and IL-17 [115]. This evidence concerns the gene TNF and neoplasm.