Similarly, Lactobacillus rhamnosus GG CGMCC 1.2134 (LGG) strain inhibited the proliferation of cancerous cells in DMH-induced CRC of Sprague-Dawley rats as displayed by the upregulated expressions of apoptotic genes such as Bax, caspase 3 and p53. This evidence concerns the gene BAX and colorectal carcinoma.