Also, clusterin, proteasome subunit alpha type 1 (PSA1), leucine aminopeptidase 3 (LAP3), annexin A3 (ANXA3), maspin (serpin B5), olfactomedin 4 (OLFM4), CD11b, integrin α2 (ITGA2), periostin, thrombospondin-2, serine/threonine kinase 4 (STK4), S100 calcium-binding protein A9 (S100A9) and macrophage mannose receptor 1 (MRC1) were overexpressed in primary CRC tumors [31, , , -35]. The gene discussed is LAP3; the disease is colorectal carcinoma.