As with the analyses reported above using the knockdown lines, Peds1 deficiency resulted in reduced plasmalogens levels and increased precursors (low levels of plasmalogen remained, likely due their acquisition from the mutant mother, who obtains them from her diet; Fig. 6B), slight developmental delay (Fig. 6C), neutropenia (Fig. 6D), monocytopenia (Fig. 6E), and exacerbated inflammation, assayed as increased transcript levels of nfkb1, il1b, tnfa and cxcl8a genes (Fig. 6F), at 3 dpf. This evidence concerns the gene IL1B and Decreased total monocyte count.