The in vivo anti-AML effects of bithionol were assessed in a leukaemia xenograft model using NSG mice engrafted with KG-1a cells, and anti-human CD45 (hCD45) and anti-mouse CD45 (mCD45) antibodies were used to quantify human leukaemic blasts and mouse leucocytes, respectively (Fig. 3). Here, PTPRC is linked to leukemia.