γδ T cells possess unconventional T-cell features that include major histocompatibility complex-dependent antigen presentation and using NK cell receptors to directly kill target cells.35 36 The antitumor function of γδ T cells is mainly associated with their cytotoxic potential and cytokine production, but also tumor-promoting functions of γδ T cells have been described.37 38 Subtypes of γδ T cells can be classified based on TCR-γ-chain variable region (Vγ) expression. This evidence concerns the gene KLRD1 and neoplasm.