Among the 16 luminal BC patients, there were two BRCA1 P/LP variant carriers: one frameshift, c.5266dup; p.Q1777fs, and one splice-site variant c.441+2T>A;, plus one BRCA2 P/LP variant carrier, a stop-codon gain (c.250C>T) (Table 3). Here, BRCA1 is linked to breast cancer.