One tumor presented three driver genes, consisting of GATA3 (dual role), PIK3CA (oncogene), and GRHL2 (gene other than CGC); another tumor, presented two driver genes represented by NF1 (TSG) and CACNA1E (gene other than CGC); and the third one, did not present any potential drivers among the sequenced gene panel. The gene discussed is PIK3CA; the disease is neoplasm.