ELANE and lobular neoplasia: Figure 1 shows that neutrophil elastase (P = 0.004), olfactomedin-4 (P = 0.002), lactoferrin (P = 0.0005), MMP-9 (P = 0.003), α-1AG (P = 0.01), and cathelicidin (P = 0.002) were significantly increased in the urine from patients with LN, compared with HDs.