In the present study, we compared [68Ga]Ga-/[18F]F-PSMA-11/-1007, 2-[18F]FDG and [68Ga]Ga-FAPI-46 tumour/stromal uptake in mCRPC patients undergoing screening for [177Lu]Lu-PSMA-617 RLT eligibility. This evidence concerns the gene FOLH1 and neoplasm.