GHRHR and cancer: In this study we have utilized a structure-basedapproach to target GHRHR with the aim of identifying compounds thatmay provide a starting point for further refinement with the potentialto produce effective therapeutic small molecules targeting the GHRHR.As GHRHR-targeted peptide antagonists have demonstrated effectivenessin several cancer models, such small-molecule alternatives would likelydisplay similar antimitogenic effects and thus would provide attractivetherapeutic options.