VTCN1 and neoplasm: Furthermore, the increased lethality of B7‐H4 and USP10 depletion tumor cells upon SG treatment appears to be linked to the induction of endoplasmic reticulum (ER) stress and the upregulation of DAMPs, such as calreticulin (CALR), heat shock proteins 70 and 90 (HSP70 and HSP90), as evidenced by flow cytometry analysis (Figure 6F–J).