FEN1 and RBX1 are two genes related to DNA repair, which have been reported to be associated with drug resistance in several cancers.[26, 27, 28] COX8A, or Cytochrome C Oxidase Subunit 8A, is a nuclear‐encoded subunit of cytochrome coxidase (COX), which is the terminal enzyme complex of the mitochondrial respiratory chain. Here, FEN1 is linked to cancer.