YAP1 and cancer: For example, yes-associated protein (YAP, also known as YAP1) and transcriptional co-activator with PDZ-binding motif (TAZ, also known as tafazzin) are components of the Hippo signalling pathway, which is involved in the regulation of cell proliferation and apoptosis and has been associated with cancer progression and metastasis (Yamaguchi and Taouk, 2020).