SAMHD1 and B-cell chronic lymphocytic leukemia: Additionally, recurrent SAMHD1 mutations have been found in a variety of haematological malignancies, such as chronic lymphocytic leukaemia (CLL) (Clifford et al., 2014; Landau et al., 2013; Schuh et al., 2012), T-cell prolymphocytic leukaemia (Johansson et al., 2018) and mantle cell lymphoma (Buhler et al., 2021; Nadeu et al., 2020; Roider et al., 2021; Wang et al., 2021).