It has been reported to possess anti‐tumor properties and various immune‐stimulating activities.[9] By binding to Macrophage‐Inducible C‐Type Lectin (Mincle), TDM triggers inflammation, mediates infective granuloma formation, and subsequently leads to fibrosis.[10] Research on the anti‐tumor effects of TDM primarily focuses on immunomodulatory, such as activating dendritic cells and CD8+ T cells to induce anti‐tumor immunity.[9] However, the impact of TDM on tumor cells themselves and its ability to induce fibroblast‐like transformation in tumor cells remains unclear. Here, CD8A is linked to neoplasm.