ELN and neoplasm: Tumor fibrosis typically represents the process of extracellular matrix (ECM) remodeling in the tumor microenvironment, with the main ECM components including collagen proteins (primarily type I and type III), elastin, and proteoglycans.[2] It is currently believed that tumor fibrosis is driven by stromal components, with research on this process mainly focusing on cancer‐associated fibroblasts (CAFs).